Table 2 Prediction of an acute event of recurrent venous thromboembolism by miR-29a and miR-let7a in an independent validation cohort of individuals with acute index event.

From: Circulating miR-let7a levels predict future diagnosis of chronic thromboembolic pulmonary hypertension

 

Hazard ratio [95% CI]

p-value

miR-29a-3p (SD)

1.29 [1.06–1.55]

0.0093

miR-let7a (SD)

0.72 [0.60–0.86]

0.0003

  1. Results of two separate Cox regression models predicting the combined endpoint of recurrent VTE or death using standardized miRNA expression levels, adjusted for age and sex. The validation cohort subsample with miRNA sequencing comprised 181 individuals, 117 of whom experienced recurrent events or died during the follow-up period (median [IQR]: 2.6 [0.7–3.2] years, max.: 7.9 years).
  2. CI confidence interval, IQR interquartile range, SD standard deviation.
Back to article page