Table 2 Results from two-way ANOVA testing the variables gene (WT and LRRK2-KO rats) and drug (vehicle and PFE360).

From: Knocking out the LRRK2 gene increases sensitivity to wavelength information in rats

 

Two-way ANOVA

 

F value

Adjusted p value (if p < 0.05)

Amplitude of peaks in the superior colliculus

 P1

Gene

F(1,27)

6.5

0.019

Drug

F(1,273)

0.0070

 

 N1

Gene

F(1,27)

14

0.0012

Drug

F(1,273)

0.065

 

 P2

Gene

F(1,27)

1.7

 

Drug

F(1,273)

0.87

 

interaction

F(1,273)

13

0.00064

 N2

Gene

F(1,27)

0.96

 

Drug

F(1,273)

20

0.00021

 P3

Gene

F(1,27)

0.66

 

Drug

F(1,273)

5.5

0.021

Latency of peaks in the superior colliculus

 P1

Gene

F(1,27)

8.3

0.009

Drug

F(1,273)

137

0.00021

 N1

Gene

F(1,27)

3.2

 

Drug

F(1,273)

84

0.00021

 P2

Gene

F(1,27)

19

0.00036

Drug

F(1,273)

14

0.00036

interaction

F(1,273)

3.9

0.049

 N2

Gene

F(1,27)

7.3

0.013

Drug

F(1,273)

12

0.00076

 P3

Gene

F(1,27)

3.1

 

Drug

F(1,273)

25

0.00021

  1. Effects on the amplitudes and latencies of visual evoked potentials from the superior colliculus were evaluated. The p values were adjusted using the FDR for all 24 ANOVAs.