Table 1 Characteristics of critically ill patients at admission in the intensive care unit according in the 4 groups.

From: Comparison of mortality and outcomes of four respiratory viruses in the intensive care unit: a multicenter retrospective study

 

Total n = 807

RSV n = 151

COVID-19 n = 332

Seasonal influenza n = 258

H1N1 influenza n = 66

P

Age (years)

70 [60; 79]

72 [60; 79]

68 [59; 77]

72 [62; 81]

66 [55; 74]

0.001

Sex (male)

501 (62)

89 (59)

239 (72)

127 (49)

46 (67)

 < 0.001

BMI (Kg.m-2)

27 [23; 30]

26 [23; 30]

27 [24; 31]

26 [22; 31]

25 [22; 28]

 < 0.001

CCI

2 [1; 4]

5 [3; 7]

1 [0; 2]

2 [1; 4]

2 [1; 3]

 < 0.001

Young and previously healthy

39 (5)

4 (3)

21 (6)

8 (3)

6 (9)

0.094

Arterial hypertension

421 (52)

62 (41)

181 (55)

142 (55)

36 (54)

0.024

Myocardial infarction

122 (15)

38 (25)

30 (9)

43 (17)

11 (17)

 < 0.001

Congestive heart failure

180 (22)

70 (46)

35 (11)

62 (24)

13 (20)

 < 0.001

Arteriopathy of lower limbs

67 (8)

11 (7)

19 (6)

29 (11)

8 (12)

0.065

Cerebral stroke

37 (5)

4 (3)

28 (8)

22 (8)

7 (11)

0.046

Hemiplegia

27 (3)

3 (2)

6 (2)

15 (6)

3 (4)

0.038

Dementia

35 (4)

3 (2)

13 (4)

16 (6)

3 (4)

0.232

Cirrhosis

28 (3)

6 (4)

7 (2)

12 (5)

3 (4)

0.283

Chronic kidney disease

47 (6)

14 (9)

11 (3)

14 (5)

8 (12)

0.007

Chronic dialysis

37 (5)

9 (6)

8 (2)

12 (5)

8 (12)

0.007

Immunosuppressive treatment

114 (14)

28 (18)

18 (5)

54 (21)

14 (21)

 < 0.001

Hospital stay within 12 months

280 (35)

86 (58)

55 (17)

113 (44)

26 (39)

 < 0.001

Diabetes

215 (27)

45 (29)

92 (28)

64 (25)

14 (21)

0.493

COPD/asthma

226 (28)

67 (44)

36 (11)

106 (41)

17 (26)

 < 0.001

Current or former smoker

310 (39)

69 (47)

100 (30)

108 (42)

33 (50)

 < 0.001

Chronic alcoholism

97 (12)

13 (9)

27 (8)

40 (15)

17 (26)

 < 0.001

Cancer in remission for more than 5 years

87 (11)

3 (2)

31 (9)

46 (18)

7 (11)

 < 0.001

Active solid cancer

99 (12)

37 (24)

16 (5)

36 (14)

10 (15)

 < 0.001

Metastatic active solid cancer

33 (4)

14 (9)

4 (1)

13 (5)

2 (3)

 < 0.001

Leukemia

13 (2)

4 (3)

0 (0)

8 (3)

1 (1)

0.003

Lymphoma

36 (4)

4 (3)

11 (3)

15 (6)

6 (9)

0.09

SAPS-II score

43 [33; 57]

51 [39; 71]

37 [28; 68]

45 [38; 61]

51 [41; 63]

 < 0.001

SOFA score at admission

6 [3; 10]

8 [4; 11]

4 [2; 8]

8 [5; 11]

9 [5; 12]

 < 0.001

Fever at admission

519 (68)

48 (35)

258 (84)

165 (65)

48 (78)

 < 0.001

  1. Data are presented as median [IQR] or n (%).COPD, chronic obstructive pulmonary disease; SAPS-II, Simplified acute physiology score; SOFA, sepsis-related organ failure assessment. P value are estimated for the heterogeneity among the four groups.
  2. Significant values are in bold.