Table 5 Areas under the receiver operating characteristic curve (AUROCs) for discrimination of preperimetric glaucoma (PPG) from normal control.

From: Hemifield-based analysis of pattern electroretinography in normal subjects and patients with preperimetric glaucoma

 

AUROC

95% CI

P-value

Lower bound

Upper bound

SD-OCT average RNFL thickness

 Total

0.898

0.824

0.972

0.026a

 Superior

0.846

0.751

0.941

0.031b

 Inferior

0.910

0.841

0.979

0.019c

SD-OCT thinner/thicker HF RNFL thickness ratio

0.687

0.552

0.821

0.822d

SD-OCT average GCIPL thickness

 Total

0.838

0.742

0.933

0.186a

 Superior

0.797

0.688

0.906

0.190b

 Inferior

0.806

0.704

0.909

0.396c

SD-OCT thinner/thicker HF GCIPL thickness ratio

0.834

0.737

0.931

0.031d

SAP MD

0.384

0.247

0.521

0.188a

SAP PSD

0.589

0.448

0.729

0.104a

PERG N95 Amplitude

 Full field

0.738

0.615

0.861

N/A

 Upper field

0.744

0.622

0.866

N/A

 Lower field

0.689

0.560

0.819

N/A

PERG smaller/larger HF N95 amplitude ratio

0.663

0.530

0.796

N/A

PERG P50 Amplitude

 Full field

0.680

0.546

0.814

0.103a

 Upper field

0.619

0.481

0.756

0.202c

 Lower field

0.582

0.439

0.726

0.033b

PERG smaller/larger HF P50 amplitude ratio

0.534

0.391

0.677

0.175d

  1. Bold indicates that the P value reached statistical significance (< 0.05).
  2. AUROC, Area Under the Receiver Operating Characteristic Curve; PPG, preperimetric glaucoma; CI, confidence interval; SD-OCT, spectral-domain optical coherence tomography; RNFL, retinal nerve fiber layer; HF, hemifield; GCIPL, ganglion cell–inner plexiform layer; SAP = standard automated perimetry; MD, mean deviation; PSD, pattern standard deviation; PERG, pattern electroretinogram.
  3. aP value: Comparison of each parameter with FF PERG N95 amplitude.
  4. bP value: Comparison of each parameter with LF PERG N95 amplitude.
  5. cP value: Comparison of each parameter with UF PERG N95 amplitude.
  6. dP value: Comparison of each parameter with smaller/larger HF PERG N95 amplitude ratio.