Table 4 Assessment of the gene expression levels of cGAS and STING and plasma levels of the investigated cytokines according to the number of symptoms and the presence and absence of comorbidities in the group with long COVID.
From: Severe COVID-19 and long COVID are associated with high expression of STING, cGAS and IFN-α
Variables | cGAS (RQ) | STING (RQ) | IFN-α (pg/mL) | TNF-α (pg/mL) | IL-6 (pg/mL) |
---|---|---|---|---|---|
Median (IIQ) | Median (IIQ) | Median (IIQ) | Median (IIQ) | Median (IIQ) | |
Number of symptoms | |||||
2 a 4 | 0.28 (0.45) | 0.05 (0.29) | 1.90 (7.14) | 8.24 (2.26) | 7.85 (0.64) |
5 a 7 | 0.72 (1.50) | 0.19 (0.74) | 10.50 (17.90) | 8.56 (2.88) | 8.42 (2.94) |
8 a 10 | 0.35 (0.19) | 0.18 (0.80) | 21.30 (19.37) | 8.24 (2.26) | 7.70 (2.49) |
p | 0.5080 | 0.6097 | 0.4342 | 0.9857 | 0.8519 |
Comorbidities | |||||
Present | 0.242 (0.43) | 0.139 (0.17) | 4.62 (12.12) | 8.01 (1.69) | 8.06 (3.12) |
Absent | 0.437 (1.94) | 0.297 (0.97) | 11.70 (21.60) | 8.96 (2.67) | 8.01 (1.75) |
p | 0.2382 | 0.3541 | 0.5474 | 0.9899 | 0.8739 |