Figure 2
DKK1 and SOST are closely negatively correlated. (A) compares DKK1 and SOST levels in healthy controls, patients immediately after traumatic long bone fracture as well as the aspirated fracture hematoma. (B) compares time course of DKK1 and SOST during fracture healing and arrows indicate their peak (respective medians and standard deviations are illustrated as line diagram for better visualization of time course in (C)—inverse correlation—P = 0.009). (D) compares DKK1 and SOST levels time course in patients with and without dysfunctional bone healing (respective medians and standard deviations are illustrated as line diagram for better visualization of time course in E). *P < 0.05, **P < 0.005.
