Table 1 Patient demographics.
Fracture cohort (N = 114/100%) | Controls (N = 33/100%) | |
|---|---|---|
Parameter | Median (IQR)/N (%) | Median (IQR)/% |
Age (years) | 43.5 (32.75–58) | 34.5 (29–46) |
Sex | ||
Female | 51.3% | 55.9% |
Male | 48.7% | 44.1% |
Fracture location | ||
Femur | 19.18% | |
Lower leg | 45,86% | |
Femur + lower leg | 7.02% | |
Humerus | 20.05% | |
Forearm | 7.89% | |
Type of fixation | ||
Plate | 33.33% | |
IM | 57.89% | |
Ex. Fix | 7.08% | |
Screw | 1.70% | |
Soft tissue damage | 14.91% | |
Non Union (N = 7) | 8.2% | |
Non osteogenic risk factors | ||
Smoking | 29.6% | |
Diabetes | 14.8% | |
Frequent alcohol intake | 7.4% | |
DKK1 (pmol/L) | ||
BL | 19.82 (16.06–26.77) | |
Week 1 | 20.68 (16.82–31.26) | |
Week 2 | 27.22 (21.92–33.77) | |
Week 4 | 21.31 (17.6–27.97) | |
Week 6 | 21.21 (16.59–28.93) | |
Week 8 | 21.59 (17–26.52) | |
Week 12 | 18.18 (14.31–24.84) | |
Week 24 | 19.58 (15.15–25.9) | |
SOST (pmol/L) | ||
BL | 8.19 (5.39–14.03) | |
Week 1 | 15.29 (10.7–22.36) | |
Week 2 | 17.81 (12.65–26.24) | |
Week 4 | 20.32 (15.4–27.6) | |
Week 6 | 18.32 (13.97–27.69) | |
Week 8 | 21.2 (15.98–31.79) | |
Week 12 | 19.95 (14.2–32.01) | |
Week 24 | 18.24 (13.7–27.65) | |
