Table 2 Transplantation details of patients with hepatitis‑associated aplastic anaemia (HAAA).
Characteristics | HAAA n = 35 |
---|---|
Interval from diagnosis to HSCT, days, median (range) | 75 (34–412) |
IST before HSCT | |
ATG-based | 2 (5.7%) |
CsA-based | 22 (62.9%) |
No | 11 (31.4%) |
HCT-CI pre-HSCT | |
0–1 | 32 (100.0%)a |
≥ 2 | 0 (0.0%)a |
Graft type | |
PB only | 29 (82.9%) |
PB + BM | 5 (14.3%) |
BM only | 1 (2.9%) |
Blood type | |
Match | 24 (68.6%) |
Major mismatch | 2 (5.7%) |
Minor mismatch | 5 (14.3%) |
Mismatch | 4 (11.4%) |
Donor–patient sex match | |
Female to female | 6 (17.1%) |
Female to male | 7 (20.0%) |
Male to male | 16 (45.7%) |
Male to female | 6 (17.1%) |
HLA type | |
5/10 | 10 (31.3%)a |
6/10 | 1 (3.1%)a |
7/10 | 3 (9.4%)a |
8/10 | 2 (6.3%)a |
9/10 | 0 (0.0%)a |
10/10 | 16 (50.0%)a |
Conditioning regimen | |
Bu + Cy + Flu + ATG | 6 (17.1%) |
Cy + Flu + ATG | 29 (82.9%) |
GVHD prophylaxis | |
CsA + MTX + MMF | 12 (37.5%) |
FK506 + MTX + MMF | 2 (6.3%) |
CsA + MTX | 15 (46.9%) |
FK506 + MTX | 3 (9.4%) |
Cell compositions in allografts | |
MNC, 108/kg | 10.00 (8.02–11.90) |
CD34+ cells, 106/kg | 2.92 (2.29–4.16) |
CD3+ T cells, 106/kg | 169.17 (109.67–230.26) |
CD3+ CD4+ T cells, 106/kg | 86.57 (56.60–123.30) |
CD3+ CD8+ T cells, 106/kg | 64.94 (41.39–105.77) |
CD19+ B cells, 106/kg | 38.52 (17.08–66.63) |