Table 1 The known senolytic compounds Dasatinib (D), Quercetin (Q), the combination of both (D + Q), and Piperlongumine, and the targeted senescent cell types.
Compound | Targeted senescent cell types | References |
---|---|---|
Piperlongumine | Human WI fibroblasts | |
Dasatinib (D) | Human and mouse preadipocytes | |
Quercetin (Q) | HUVECs | |
D + Q | Same cells as by D or Q Primary mouse embryonic fibroblasts Bone marrow-derived mesenchymal stem cell Alveolar epithelial type II cells senescent cells in skin ulcer samples |