Table 5 Trypan blue exclusion result of % cytotoxicity at 10, 50, and 90 μg/ml concentrations (p< 0.05 mean ± SD).

From: Enhancing therapeutic efficacy: sustained delivery of 5-fluorouracil (5-FU) via thiolated chitosan nanoparticles targeting CD44 in triple-negative breast cancer

S.No

Concentration

HA-coated 5-FU in ThCs-NPs

Crude-5-FU

%Cytotoxicity MDA-MB-231

  

 1

90 µg/ml

85±0.04

77.8±0.04

 2

50 µg/ml

60.3±0.21

53.6±0.04

 3

10 µg/ml

35.3±0.03

32.1±0.12

 4

0 µg/ml

10±0.07

10±0.01

%Cytotoxicity MCF-10A

   

 1

90 µg/ml

25±0.03

67±0.02

 2

50 µg/ml

18.4±0.02

46±0.03

 3

10 µg/ml

12±0.05

29.7±0.04

 4

0 µg/ml

10±0.07

11±0.04