Figure 6 | Scientific Reports

Figure 6

From: Integrating X-ray phase-contrast imaging and histology for comparative evaluation of breast tissue malignancies in virtual histology analysis

Figure 6

Hybrid visualization of conventional 2D histology slide and 3D PhC virtual histology image data volume of the invasive lobular carcinoma specimen. The area of the bottom slice is equal to \(\sim\) 8 mm \(\times \sim\) 8 mm, while the histological cut slice area is 2.4 mm \(\times\) 1.4 mm (the thickness is around 5 μm). The rendered portion of the specimen volume is: 2.4 mm \(\times\) 1.4 mm \(\times\) 1.2 mm. Comparing the size of the images obtained with the two techniques it becomes evident that the histological section is representative of only a very small portion of the sample analyzed. The histological section is co-registered with the corresponding PhC \(\mu\)CT slice showing that images obtained with the two techniques can be combined and/or fused together. The volume rendering has been generated by using Avizo® 3D software version.

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