Table 4 Relationship between ALT/HDL-C ratio and the incident NAFLD in different models.

From: Association between alanine aminotransferase to high-density lipoprotein cholesterol ratio and nonalcoholic fatty liver disease: a retrospective cohort study in lean Chinese individuals

Variable

Model 1 (HR, 95% CI, P)

Model 2 (HR, 95% CI, P)

Model 3 (HR, 95% CI, P)

Model 4 (HR, 95% CI, P)

ALT/HDL-C ratio

1.052 (1.048, 1.055) < 0.001

1.034 (1.030, 1.038) < 0.001

1.037 (1.031, 1.042) < 0.001

1.028 (1.022, 1.034) < 0.00001

ALT/HDL-C ratio (quartile)

 Q1

Ref

Ref

Ref

Ref

 Q2

2.317 (1.873, 2.867) < 0.001

1.796 (1.451, 2.223) < 0.001

1.795 (1.447, 2.226) < 0.001

1.580 (1.270, 1.965) < 0.001

 Q3

4.727 (3.886, 5.750) < 0.001

3.011 (2.472, 3.668) < 0.001

2.951 (2.408, 3.618) < 0.001

2.350 (1.899, 2.909) < 0.001

 Q4

8.440 (6.987, 10.195) < 0.001

4.469 (3.688, 5.416) < 0.001

4.417 (3.575, 5.457) < 0.001

3.317 (2.642, 4.164) < 0.001

P for trend

< 0.001

< 0.001

< 0.001

< 0.001

  1. Model 1: we did not adjust for other covariants.
  2. Model 2: we adjusted for DBP, gender, age, SBP, and BMI.
  3. Model 3: we adjusted for DBP, gender, age, SBP, BMI, TC, AST, UA, GGT, TG, ALP, Cr, FPG, and LDL-C.
  4. Model 4: we adjusted for DBP, gender, age, SBP, BMI, TC, AST, UA, GGT, TG, ALP, Cr, FPG, and LDL-C. However, continuous covariates were adjusted as nonlinearity.
  5. HR hazard ratio, CI confidence interval, Ref reference, ALT/HDL-C ratio alanine aminotransferase to high-density lipoprotein cholesterol ratio, NAFLD nonalcoholic fatty liver disease.
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