Table 7 Effect size of ALT/HDL-C ratio on NAFLD in prespecified and exploratory subgroups.

From: Association between alanine aminotransferase to high-density lipoprotein cholesterol ratio and nonalcoholic fatty liver disease: a retrospective cohort study in lean Chinese individuals

Characteristic

No of patients

Effect size (95% CI)

P value

P for interaction

Age (years)

0.484

 < 60

10,125

1.037 (1.031, 1.043)

< 0.001

 

 ≥ 60

1850

1.033 (1.020, 1.045)

< 0.001

 

Gender

0.150

 Female

5419

1.034 (1.027, 1.041)

< 0.001

 

 Male

6556

1.039 (1.033, 1.046)

< 0.001

 

BMI (kg/m2)

< 0.001

 < 24

10,382

1.057 (1.051, 1.064)

< 0.001

 

 ≥ 24

1593

1.030 (1.021, 1.039)

< 0.001

 

SBP (mmHg)

0.375

 < 90

10,221

1.038 (1.032, 1.044)

< 0.001

 

 ≥ 90

1754

1.033 (1.024, 1.043)

< 0.001

 

DBP (mmHg)

0.012

 < 140

10,981

1.040 (1.034, 1.045)

< 0.001

 

 ≥ 140

994

1.026 (1.015, 1.037)

< 0.001

 
  1. Note 1: Above model adjusted for we adjusted for DBP, gender, age, SBP, BMI, TC, AST, UA, GGT, TG, ALP, Cr, FPG, and LDL-C.
  2. Note 2: The model is not adjusted for the stratification variable in each case.
  3. HR hazard ratios, CI confidence, ALT/HDL-C ratio alanine aminotransferase to high-density lipoprotein cholesterol ratio, NAFLD nonalcoholic fatty liver disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure.
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