Table 2 Patient characteristics before and after IPTW compared between the thienopyridine and aspirin groups.

From: Effects of thienopyridine class antiplatelets on bleeding outcomes following robot-assisted radical prostatectomy

Parameter

Total

Unweighted study cohort

Weighted study cohort

Thienopyridine group

vs

Aspirin group

SD

Thienopyridine group

vs

Aspirin group

SD

Patients, no

520

147

 

373

     

Median age, years (IQR)

71 (68–74)

71 (67–74)

 

71 (68–74)

− 0.014

71 (67–75)

 

71 (68–74)

− 0.023

ASA PS, n (%)

 1

63 (12)

17 (11)

 

46 (12)

0.257

13%

 

12%

0.013

 2

358 (69)

91 (62)

 

267 (72)

 

67%

 

69%

 

 3, or more

99 (19)

39 (27)

 

60 (16)

 

20%

 

19%

 

BMI 25 kg/m2, n (%)

204 (39)

50 (34)

 

154 (41)

− 0.151

38%

 

39%

− 0.015

KDIGO CKD grade (eGFR), n (%)

 Grade 1, or 2 (60 mL/min/1.73 m2, or more)

333 (64)

89 (61)

 

244 (65)

0.101

65%

 

64%

− 0.020

 Grade 3a, or 3b (30–59 mL/min/1.73 m2)

172 (33)

51 (35)

 

121 (32)

 

32%

 

33%

 

 Grade 4, or 5 (29 mL/min/1.73 m2, or less)

15 (2.9)

7 (4.7)

 

8 (2.1)

 

3.4%

 

3.1%

 

NCCN risk classification group, n (%)

 Low

15 (2.9)

4 (2.9)

 

11 (3.0)

0.074

2.6%

 

3.0%

0.002

 Intermediate

257 (49)

69 (47)

 

188 (40)

 

49%

 

49%

 

 High, or more

248 (48)

74 (50)

 

174 (47)

 

48%

 

48%

 

Pelvic lymph node dissection, n (%)

 None

269 (51)

75 (51)

 

194 (52)

− 0.126

52%

 

53%

− 0.040

 Limited

144 (28)

47 (32)

 

97 (26)

 

29%

 

27%

 

 Extended

107 (21)

25 (17)

 

82 (22)

 

19%

 

20%

 

Neurovascular bundle preservation, n (%)

154 (30)

46 (31)

 

108 (29)

0.051

29%

 

29%

0.040

Preoperative hormonal therapy, n (%)

132 (25)

32 (22)

 

100 (27)

− 0.118

27%

 

26%

0.024

Perioperative continuation of antiplatelets, n (%)

133 (26)

25 (17)

 

108 (29)

− 0.287

24%

 

26%

− 0.036

  1. ASA PS, American Society of Anesthesiologists physical status classification; BMI, body mass index; CKD, chronic kidney disease; eGFR, estimated glomerular filtration rate; IPTW, inverse probability of treatment weighting; IQR, interquartile range; KDIGO, kidney disease improving global outcomes; NCCN, National Comprehensive Cancer Network; SD, Standardized difference.
  2. Significant values are in bold.