Table 3 The relative risk for PPCs in patients with esophageal cancer who underwent esophagectomy by the quintiles of FEV1%pred and DLco %pred.

From: Preoperative DLco and FEV1 are correlated with postoperative pulmonary complications in patients after esophagectomy

 

FEV1%pred

P for trend

Quintile 1

(n = 165)

 ≤ 78

Quintile 2

(n = 165)

 > 78– ≤ 87

Quintile 3

(n = 171)

 > 87– ≤ 94

Quintile 4

(n = 155)

 > 94– ≤ 103

Quintile 5

(n = 154)

 > 103– ≤ 139

Crude

2.41 (1.49–3.90)

1.87 (1.13–3.09)

1.47 (0.87–2.49)

1.15 (0.65–2.04)

Reference

 < 0.01

Adjusteda

2.05 (1.24–3.38)

1.69 (1.02–2.82)

1.55 (0.92–2.62)

1.17 (0.66–2.06)

Reference

 < 0.01

IPTW

2.72 (1.60–4.64)

1.98 (1.12–3.48)

1.66 (0.93–2.97)

1.30 (0.70–2.42)

Reference

 < 0.01

 

DLco %pred

P for trend

Quintile 1

(n = 166)

 ≤ 72

Quintile 2

(n = 171)

 > 72– ≤ 83

Quintile 3

(n = 160)

 > 83– ≤ 92

Quintile 4

(n = 153)

 > 92– ≤ 102

Quintile 5

(n = 160)

 > 102– ≤ 148

Crude

3.35 (2.04–5.48)

1.98 (1.16–3.38)

1.59 (0.90–2.80)

1.23 (0.67–2.26)

Reference

 < 0.01

Adjusteda

2.98 (1.72–5.15)

1.88 (1.08–3.26)

1.59 (0.89–2.82)

1.24 (0.68–2.28)

Reference

 < 0.01

IPTW

2.83 (1.63–4.92)

1.83 (1.01–3.30)

1.57 (0.84–2.93)

0.90 (0.45–1.79)

Reference

 < 0.01

  1. Data are presented as a ratio (95% confidence interval).
  2. PPCs, postoperative pulmonary complications; FEV1, forced expiratory volume in 1 s; %pred, %predicted; Quintile 1, the lowest quintile; Quintile 5, the top quintile; DLco, diffusing capacity of the lung for carbon monoxide, IPTW, inverse probability treatment weight.
  3. aAdjusted for age, sex, body mass index, smoking status (never and ever), chronic pulmonary disease, cardiovascular disease, albumin, pathologic stage (I, II, and III), tumor location (cervical/upper thoracic, middle thoracic, and lower thoracic/esophagogastric junction), type of surgery (open thoracotomy, video-assisted thoracoscopic, and robotic surgery), lymph node dissection (two-field or less and three-field), operation time.
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