Table 2 Comparison of clinical symptoms, nutritional status, exercise endurance, grip strength and malnutrition rate among different COPD grades.

From: Prediction model and assessment of malnutrition in patients with stable chronic obstructive pulmonary disease

 

Grade I

Grade II

Grade III

Grade IV

P value

N

81

88

63

19

 

Age (years)

62.48 ± 8.95b

65.09 ± 8.58ab

66.65 ± 7.04a

67.74 ± 5.90a

0.007

Height (cm)

168.41 ± 6.50

168.31 ± 6.50

167.52 ± 6.26

167.26 ± 5.26

0.772

Handgrip (kg)

40.54 ± 6.78a

35.64 ± 6.88b

31.93 ± 5.32c

27.18 ± 6.28d

 < 0.001

6MWD (m)

572.79 ± 47.61a

528.18 ± 51.22b

488.91 ± 78.16c

368.32 ± 74.76d

 < 0.001

AE (times)

0 (0,1)d

1 (0,2)c

2 (1,3)b

4 (4,6)a

 < 0.001

CAT

5 (3,9)c

9 (5,13)b

17 (12,20)a

20 (17,24)a

 < 0.001

mMRC

0 (0,1)c

1 (0,2)b

2 (2,3)a

3 (3,3)a

 < 0.001

BMI (kg/m2)

23.82 ± 2.87ab

23.89 ± 2.80a

22.62 ± 3.17bc

21.04 ± 3.27c

 < 0.001

VFA > 100cm2

14 (17.28%)

15 (17.05%)

15 (23.81%)

3 (15.79%)

0.809

WHR

0.87 (0.84,0.92)

0.85 (0.83,0.92)

0.88 (0.85,0.90)

0.88 (0.85,0.93)

0.395

SMM (kg)

28.08 ± 3.90a

27.57 ± 3.62a

25.49 ± 3.30b

23.73 ± 3.56b

 < 0.001

FFMI (kg/m2)

17.93 ± 1.45a

17.65 ± 1.41a

16.64 ± 1.42b

15.64 ± 1.69c

 < 0.001

Malnutrition

25 (30.86%)b

32 (36.36%)b

40 (63.49%)a

14 (73.68%)a

 < 0.001

  1. 6MWD 6-min walk distance, AE acute exacerbations during the past year, BMI body mass index, VFA visceral fat area, WHR waist-to-hip ratio, FFMI fat-free mass index, SMM skeletal muscle mass.
  2. *The significant differences between different grades were compared and shown by letter marking method. Data exhibiting significant differences (p < 0.05) are denoted by different letters.
  3. Significant values are in bold.