Table 3 Cardiovascular events and all-cause mortality according to RBC transfusion and ESA therapy.
No. patients | No. of events (% per patient-year) | Crude HR (95% CI) | Adjusted* HR (95% CI) | |
|---|---|---|---|---|
Cardiovascular events† | ||||
Control | 2428 | 141 (1.6) | Reference | Reference |
RBC transfusion | 5948 | 309 (1.8) | 1.08 (0.88–1.32) | 1.00 (0.80–1.24) |
ESA | 270 | 157 (2.6) | 1.46 (1.16–1.83) | 1.23 (0.96–1.57) |
RBC transfusion and ESA | 2277 | 15 (1.7) | 1.01 (0.61–1.65) | 0.88 (0.54–1.42) |
All-cause mortality | ||||
Control | 2428 | 771 (8.4) | Reference | Reference |
RBC transfusion | 5948 | 3107 (17.5) | 1.93 (1.78–2.10) | 1.53 (1.40–1.66) |
ESA | 270 | 83 (9.2) | 0.99 (0.80–1.21) | 0.78 (0.64–0.97) |
RBC transfusion and ESA | 2277 | 1133 (17.7) | 1.83 (1.67–2.00) | 1.23 (1.13–1.34) |
