Table 1 Comparison of baseline characteristics between subjects with and without NAFLD.
NAFLD (-) (n = 3676) | NAFLD ( +) (n = 2253) | P value | |
|---|---|---|---|
Age, years | 48.7 ± 10.9 | 51.4 ± 9.9 | < 0.001 |
Male gender | 1571 (42.7%) | 1700 (75.5%) | < 0.001 |
Non smoking | 2099 (65.5%) | 857 (41.6%) | < 0.001 |
Ex-smoking | 745 (23.3%) | 778 (37.8%) | |
Current smoking | 360 (11.2%) | 424 (20.6%) | |
Antidiabetic medication | 55 (1.5%) | 127 (5.6%) | < 0.001 |
Antihypertensive medication | 303 (8.2%) | 402 (17.8%) | < 0.001 |
Medication for dyslipidemia | 210 (5.7%) | 273 (12.1%) | < 0.001 |
Exercise amount (rigorous) | 223 (6.1%) | 99 (4.4%) | 0.007 |
Metabolic syndrome | 222 (6.2%) | 732 (33.0%) | < 0.001 |
Body mass index, kg/m2 | 21.8 ± 2.6 | 24.9 ± 2.8 | < 0.001 |
Waist circumference, cm | 78.5 ± 7.7 | 87.8 ± 7.5 | < 0.001 |
Triglycerides, mg/dL | 83.1 ± 45.5 | 134.0 ± 84.5 | < 0.001 |
HDL cholesterol, mg/dL | 56.9 ± 12.3 | 48.5 ± 9.5 | < 0.001 |
LDL cholesterol, mg/dL | 117.7 ± 28.5 | 127.3 ± 30.4 | < 0.001 |
Fasting glucose, mg/dL | 93.7 ± 12.3 | 103.5 ± 20.1 | < 0.001 |
HbA1c, % | 5.5 ± 0.4 | 5.8 ± 0.7 | < 0.001 |
GGT, U/L | 23.6 ± 21.2 | 39.3 ± 35.3 | < 0.001 |
AST, U/L | 21.9 ± 9.3 | 25.7 ± 12.0 | < 0.001 |
ALT, U/L | 18.8 ± 11.8 | 30.7 ± 20.6 | < 0.001 |
ALP, U/L | 51.6 ± 14.4 | 56.1 ± 14.5 | < 0.001 |
WBC, k/ul | 5.1 ± 1.5 | 5.7 ± 1.5 | < 0.001 |
Platelet count, k/ul | 235.0 ± 52.3 | 237.0 ± 54.9 | 0.167 |
Mean platelet volume (MPV) | 8.6 ± 0.8 | 8.5 ± 0.7 | < 0.001 |
WBC/MPV | 0.6 ± 0.2 | 0.7 ± 0.2 | < 0.001 |
Platelet-lymphocyte ratio (PLR) | 153.9 ± 53.2 | 137.1 ± 47.7 | < 0.001 |
Lymphocyte-monocyte ratio (LMR) | 6.8 ± 2.3 | 6.7 ± 2.1 | 0.008 |