Table 1 Comparison of baseline characteristics between subjects with and without NAFLD.

From: The association between platelet-related parameters and nonalcoholic fatty liver disease in a metabolically healthy nonobese population

 

NAFLD (-) (n = 3676)

NAFLD ( +) (n = 2253)

P value

Age, years

48.7 ± 10.9

51.4 ± 9.9

 < 0.001

Male gender

1571 (42.7%)

1700 (75.5%)

 < 0.001

Non smoking

2099 (65.5%)

857 (41.6%)

 < 0.001

Ex-smoking

745 (23.3%)

778 (37.8%)

Current smoking

360 (11.2%)

424 (20.6%)

Antidiabetic medication

55 (1.5%)

127 (5.6%)

 < 0.001

Antihypertensive medication

303 (8.2%)

402 (17.8%)

 < 0.001

Medication for dyslipidemia

210 (5.7%)

273 (12.1%)

 < 0.001

Exercise amount (rigorous)

223 (6.1%)

99 (4.4%)

0.007

Metabolic syndrome

222 (6.2%)

732 (33.0%)

 < 0.001

Body mass index, kg/m2

21.8 ± 2.6

24.9 ± 2.8

 < 0.001

Waist circumference, cm

78.5 ± 7.7

87.8 ± 7.5

 < 0.001

Triglycerides, mg/dL

83.1 ± 45.5

134.0 ± 84.5

 < 0.001

HDL cholesterol, mg/dL

56.9 ± 12.3

48.5 ± 9.5

 < 0.001

LDL cholesterol, mg/dL

117.7 ± 28.5

127.3 ± 30.4

 < 0.001

Fasting glucose, mg/dL

93.7 ± 12.3

103.5 ± 20.1

 < 0.001

HbA1c, %

5.5 ± 0.4

5.8 ± 0.7

 < 0.001

GGT, U/L

23.6 ± 21.2

39.3 ± 35.3

 < 0.001

AST, U/L

21.9 ± 9.3

25.7 ± 12.0

 < 0.001

ALT, U/L

18.8 ± 11.8

30.7 ± 20.6

 < 0.001

ALP, U/L

51.6 ± 14.4

56.1 ± 14.5

 < 0.001

WBC, k/ul

5.1 ± 1.5

5.7 ± 1.5

 < 0.001

Platelet count, k/ul

235.0 ± 52.3

237.0 ± 54.9

0.167

Mean platelet volume (MPV)

8.6 ± 0.8

8.5 ± 0.7

 < 0.001

WBC/MPV

0.6 ± 0.2

0.7 ± 0.2

 < 0.001

Platelet-lymphocyte ratio (PLR)

153.9 ± 53.2

137.1 ± 47.7

 < 0.001

Lymphocyte-monocyte ratio (LMR)

6.8 ± 2.3

6.7 ± 2.1

0.008

  1. HDL, high-density lipoprotein; LDL, low-density lipoprotein; HbA1c, hemoglobin A1c; Data are presented as the mean ± standard deviation or number (%).
  2. There are missing data of platelet-related parameters (n = 26), WBC related parameters (n = 26) and metabolic syndrome (n = 112).