Table 1 Results of Cox proportional hazard model for hydrophilic metabolome data.

From: Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort

Class

Rate of MCI patients (24 month)

Hazard ratio

P-value

Ergothioneine > − 0.360

81%

–

–

Ergothioneine ≤ − 0.360

69%

1.7

0.012

Palmitoleamide ≤ − 0.372

82%

–

–

Palmitoleamide > − 0.372

69%

2

0.001

Oleamide ≤ − 0.308

81%

–

–

Oleamide > − 0.308

69%

1.8

0.002

DG 16:0_18:2 ≤ − 0.194

80%

–

–

DG 16:0_18:2 > − 0.194

69%

1.7

0.007

  1. The rate of MCI patients indicates the rate of those who retained MCI status at 24 months from baseline. A hyphen (–) indicates control. P-values and hazard ratios were calculated compared to a control group. P-values were calculated using the Wald test.
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