Figure 5
From: Possible involvement of zinc transporter ZIP13 in myogenic differentiation
ZIP13 is involved in normal myogenic differentiation. ZIP13 is upregulated under myogenic stimulation, most likely through myogenic regulatory factors (MRFs) including MyoD and Myogenin. In addition, ZIP13 and MRFs, namely MyoD and Myogenin, are required for induction with each other, implying that ZIP13 might have a role to amplify the expression loop of MRFs leading the accurate myogenic differentiation.
