Table 4 Univariate and multivariate Cox proportional hazards model for predictors of the primary outcomes.
Univariate model | Multivariate model 1 | Multivariate model 2 | |||||||
|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | HR | 95% CI | P value | |
Renal category | |||||||||
No AKI | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference | Reference |
Transient AKI | 3.07 | 1.80–5.24 | < 0.0001 | 1.45 | 0.78–2.71 | 0.24 | 1.54 | 0.84–2.81 | 0.16 |
Persistent AKI | 6.24 | 3.48–11.21 | < 0.0001 | 2.68 | 1.41–5.10 | 0.0026 | 2.62 | 1.38–4.99 | 0.0034 |
Age > 75 | 3.36 | 2.32–4.87 | < 0.0001 | 2.83 | 1.79–4.48 | < 0.0001 | 2.76 | 1.76–4.33 | < 0.0001 |
Male gender | 0.75 | 0.50–1.14 | 0.17 | ||||||
History of MI | 2.34 | 1.31–4.16 | 0.004 | 2.19 | 1.20–4.02 | 0.011 | 2.16 | 1.18–3.96 | 0.013 |
Stroke or PAD | 3.27 | 2.08–5.13 | < 0.0001 | 2.55 | 1.55–4.18 | 0.0002 | 2.58 | 1.58–4.21 | 0.0002 |
Anemia | 2.44 | 1.68–3.52 | < 0.0001 | 1.67 | 1.06–2.64 | 0.027 | 1.71 | 1.08–2.69 | 0.0213 |
Bleeding BARC type ≥ 3 | 3.23 | 1.85–5.66 | < 0.0001 | 1.66 | 0.87–3.18 | 0.13 | 1.63 | 0.81–3.29 | 0.17 |
eGFR | 0.98 | 0.97–0.99 | < 0.0001 | 1.00 | 0.99–1.01 | 0.97 | 1.00 | 0.99–1.01 | 0.93 |
EF < 40% | 6.62 | 4.38–10.00 | < 0.0001 | 2.98 | 1.82–4.87 | < 0.0001 | 3.11 | 1.95–4.96 | < 0.0001 |
Max CKMB | 1.0011 | 1.0005–1.0017 | 0.0003 | 1.0016 | 1.0009–1.0023 | < 0.0001 | 1.0016 | 1.0008–1.0022 | < 0.0001 |
Killip ≥ 3 | 2.80 | 1.80–4.37 | < 0.0001 | 1.50 | 0.90–2.50 | 0.12 | 1.45 | 0.86–2.44 | 0.16 |
Post PCI TMI score < 3 | 2.13 | 1.19–3.79 | 0.0107 | 1.37 | 0.73–2.56 | 0.33 | |||
Mechanical circulatory support | 1.78 | 1.13–2.78 | 0.013 | 1.02 | 0.58–1.79 | 0.95 | |||
