Table 5 Univariate logistic regression for predictors of AKI and persistent AKI.

From: Prognostic impact and predictors of persistent renal dysfunction in acute kidney injury after percutaneous coronary intervention for acute myocardial infarction

 

Univariate model for AKI

Univariate model for persistent AKI

HR

95% CI

P value

HR

95% CI

P value

Male gender

0.82

0.49–1.38

0.46

0.51

0.22–1.17

0.11

Age > 75 years

2.52

1.60–3.96

< 0.0001

3.23

1.44–7.21

0.0043

Diabetes mellitus

2.00

1.28–3.14

0.0025

1.22

0.54–2.75

0.63

PAD

3.46

1.33–9.02

0.011

3.44

0.76–15.5

0.11

Anemia

3.11

1.98–4.90

< 0.0001

3.38

1.51–7.55

3.38

ARB, ACE-Is or ARNI

2.07

1.31–3.25

0.0017

1.80

0.81–4.03

0.15

Bleeding BARC type ≥ 3

5.19

2.62–10.27

< 0.0001

5.36

1.91–15.04

0.006

Killip ≥ 3

2.69

1.51–4.77

0.0008

2.22

0.81–6.07

0.12

eGFR

0.98

0.96–0.99

< 0.0001

0.977

0.958–0.997

0.0203

EF < 40%

4.43

2.46–7.99

< 0.0001

5.19

2.06–13.07

0.0005

Max CKMB

1.0008

1.0001–1.0017

0.0473

1.0014

1.0002–1.0027

0.026

Femoral artery approach

1.75

1.11–2.76

0.017

2.04

0.89–4.67

0.09

Multivessel PCI with one-time strategy

2.47

1.10–5.54

0.029

1.86

0.42–8.19

0.41

Contrast volume

0.998

0.994–1.001

0.22

0.997

0.990–1.004

0.37

Contrast volume/eGFR

1.42

1.21–1.66

< 0.0001

1.37

1.04–1.79

0.023

Mechanical circulatory support

1.77

1.01–3.10

0.0451

0.84

0.25–2.84

0.78

Mehran risk score

1.10

1.07–1.14

< 0.0001

1.060

1.001–1.121

0.0444

  1. AKI acute kidney injury, CI confidence interval, PAD peripheral artery disease, ARB angiotensin II receptor blocker, ACE-Is angiotensin-converting enzyme inhibitors, ARNI angiotensin receptor neprilysin inhibitor, BARC Bleeding Academic Research Consortium, EF ejection fraction, CK-MB creatine kinase, eGFR estimated glomerular filtration rate, MI myocardial infarction, TIMI thrombolysis in myocardial infarction.
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