Figure 4 | Scientific Reports

Figure 4

From: Caveolin-1 gene expression provides additional prognostic information combined with PAM50 risk of recurrence (ROR) score in breast cancer

Figure 4

Molecular analyses of CAV1 expression. Volcano plot showing significant up- and downregulated genes (red) in high expressing (T3) in relation to low expressing (T1) CAV1 separately by ROR High category (A) and ROR Low/Intermediate category (B). Gene Set Enrichment Analysis (GO categories) of genes ranked by fold change (log2FC) and p-value < 0.05, up- and downregulated genes (red) in high expressing (T3) in relation to low expressing (T1) CAV1 tumors separately by ROR High category (C) and ROR Low/Intermediate category (D). Categories found enriched in both subgroup analyses are indicated by red text. Dot plot showing activated and suppressed Hallmark Signatures in high expressing (T3) in relation to low expressing (T1) CAV1 tumors separately by ROR High category (E) and ROR Low/Intermediate category (F).

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