Figure 2 | Scientific Reports

Figure 2

From: Differential prognostic values of the three AKT isoforms in acute myeloid leukemia

Figure 2

Expression of each AKT transcript in AML samples. (A) Each dot shows RNA-seq normalized expression (log2 RPKM) of each AKT in samples of the IUCT-AML (left, n = 40) or the Beat-AML (right, n = 445) datasets. (B) Each dot shows expression of each AKT in AML FAB categories of the IUCT-AML (left, n = 40) or of the Beat-AML (right, n = 445) cohort. X axes: M0 = undifferentiated; M1 = myeloblastic without maturation; M2 = myeloblastic with maturation; M3 = promyelocytic; M4 = myelomonocytic; M5 = monocytic; M6 = erythroleukemia; M7 = megakaryoblastic. (C) Each dot shows expression of each AKT in hierarchical clustering categories (left, n = 281) or as a function of the PC3-34 score (right, n = 445) of the Beat-AML series of samples. X axes: PRIM = primitive; INT = intermediary; GMP = granulo-monocyte progenitor; MAT = mature. Bars represent medians with 95% CI. Trend curves are shown as dotted lines + coefficients of linear regression (r2).

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