Figure 1 | Scientific Reports

Figure 1

From: Linking alterations in estrogen receptor expression to memory deficits and depressive behavior in an ovariectomy mouse model

Figure 1

Depressive-like behaviors and memory impairment. From 4 to 12 weeks post-OVX, representative 2D tracking images (A), the time spent in the center (B), and the total distance (C) in the OFT, along with representative FST 2D tracking images (D), immobility duration (E), and total global activity (F) in the FST, and NBT images (G) and nest building score (H), were conducted to confirm that OVX induced anxiety and depressive-like behaviors in mice, respectively. In addition, the Y-maze test (I) and novel object test (J) were performed to confirm that OVX induced short- and long-term memory impairment in mice, respectively. The data were analyzed by unpaired t-test for the difference between sham and OVX at the same time-point (Each, n = 6). #p < 0.05 and ##p < 0.01 compared with the sham group.

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