Figure 3 | Scientific Reports

Figure 3

From: Linking alterations in estrogen receptor expression to memory deficits and depressive behavior in an ovariectomy mouse model

Figure 3

Alteration of microglial-derived neuroinflammation. In OVX-induced and sham mice, the protein expression of Iba-1 in the six brain regions was determined by western blotting (A), and their intensities of Iba-1 (B) at 12 weeks were semi-quantified using Image J, as well as the levels of IL-1β (C) in serum were analyzed ELISA from 4 to12 weeks. Hippo, hippocampus; PFC, prefrontal cortex, stri, striatum; RN, raphe nuclei; Amy, amygdala, and Hypo, hypothalamus. The data were analyzed by unpaired t-test for the difference between sham and OVX at the same time-point (Each, n = 6). #p < 0.05 and ##p < 0.01 compared with the sham group.

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