Figure 2 | Scientific Reports

Figure 2

From: Single-cell RNA sequencing unveils tumor heterogeneity and immune microenvironment between subungual and plantar melanoma

Figure 2

Identification and characterization of malignant cells in AM. (A) UMAP plots for the 5 subpopulations of melanocytes. (B) Average proportion of each subpopulation of melanocytes between 4 tissues. (C) Heatmap showing the top 20 DEGs (Wilcoxon test) between PM and SM. (D) Violin plots showing the CNV signals for the 12 cell types. (E) Violin plots showing the CNV signals for the 4 tissues. (F) Violin plots showing the CNV signals for the 5 malignant cell subpopulations. (G) Heatmap showing CNVs for individual cells of melanocytes. The color shows the log2 CNV ratio. Red: amplifications; blue: deletions. (H) Differences in pathway activity (scored per cell by GSVA) in 5 malignant cell subpopulations.

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