Figure 3 | Scientific Reports

Figure 3

From: Single-cell RNA sequencing unveils tumor heterogeneity and immune microenvironment between subungual and plantar melanoma

Figure 3

Detailed characterization of fibroblasts. (A) UMAP plots for the 6 subpopulations of fibroblasts. (B,C) Average proportion of each subpopulation of fibroblasts between 4 tissues. (D) Bar plot showing the number and strength of interactions between melanocytes and fibroblasts in PM1 and SM1. (E,F) Heatmap showing the number of interactions between melanocytes subpopulations and fibroblasts subpopulations in PM1 and SM1. (G) Dot plot showing receptor-ligand pair analysis of the interactions between melanocytes and fibroblasts. (H,I) Pseudotime trajectory demonstrating the transcriptome lineage of 6 fibroblasts subpopulations. Colors indicate pseudotime progression. (J) Line plot showing the development trend of module 3 in pseudotime trajectory. (K) The development trend of 4 modules of fibroblasts in pseudotime trajectory. (L) Immunofluorescence staining of EFNA1 in PM and SM.

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