Figure 2 | Scientific Reports

Figure 2

From: Comprehensive landscape of neutralizing antibody and cell-mediated response elicited by the 1/5 fractional dose of 17DD-YF primary vaccination in adults

Figure 2

Changes in systemic soluble mediators in adults following 17DD-YF 1/5 fractional dose primary vaccination. Systemic soluble mediators were measured in plasma samples from all volunteers before [NV(D0) = , n = 15] and 30–45 days after [PV(D30–45) = ▬, n = 15] 17DD-YF 1/5 fractional dose primary vaccination. Measurements were carried out by xMAP technology as described in “Methods” section. The results are shown as mean values ± standard error of plasma concentration expressed in pg/mL or MFI (#). Comparative analysis between NV(D0) and PV(D30–45) was carried out by Student t test. Significant differences at p < 0.05 are underscored according to p value (*p < 0.05; **p ≤ 0.01, ***p ≤ 0. 001). Pink background underscores the soluble mediators with increased levels in PV(D30–45) as compared to NV(D0).

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