Figure 9

The role of NKCAS in predicting immunotherapy response. (A–C) Comparison of conventional immunotherapy predictors including PD-L1, TMB, and TIDE scores in low- and high-risk groups. (D) The relationship between the response to immunotherapy and the risk scores. (E) The proportion of response to immunotherapy in low- versus high-risk group. (F) Kaplan–Meier survival curve of the low- versus high-risk group in the immunotherapy cohort (IMvigor 210 cohort). (G–H) The TMB and neoantigen burden in low- versus high-risk group. (I) Multivariate Cox regression analysis of the NCMGS with features in the immunotherapy cohort.