Table 1 Clinical characteristics of the study participants according to serum high-sensitivity C-reactive protein level (n = 10,085).
Variable | Serum hs-CRP level, mg/L | ||||
|---|---|---|---|---|---|
< 1.0 | 1.0–1.9 | 2.0–2.9 | ≥ 3.0 | P for trend | |
n = 7465 | n = 1379 | n = 442 | n = 799 | ||
Age, y | 73.5 (6.5) | 74.0 (6.8) | 74.2 (7.2) | 75.4 (7.3) | < 0.001 |
Female, % | 60.0 | 52.1 | 48.2 | 49.2 | < 0.001 |
Education ≤ 9 y, % | 31.4 | 31.6 | 33.6 | 37.2 | 0.002 |
Hypertension, % | 72.0 | 78.6 | 77.9 | 78.0 | < 0.001 |
Diabetes mellitus, % | 15.2 | 19.82 | 22.5 | 21.5 | < 0.001 |
Serum total cholesterol, mmol/L | 5.4 (0.9) | 5.3 (0.9) | 5.2 (0.9) | 5.0 (0.9) | < 0.001 |
BMI, kg/m2 | 23.0 (3.2) | 24.4 (3.5) | 24.3 (3.6) | 23.9 (3.9) | < 0.001 |
Ischemic heart disease, % | 4.2 | 5.2 | 5.4 | 7.0 | < 0.001 |
Chronic kidney disease, % | 17.4 | 23.8 | 24.7 | 26.7 | < 0.001 |
ECG abnormalities, % | 13.5 | 14.2 | 18.8 | 16.6 | 0.001 |
History of stroke, % | 5.5 | 8.5 | 7.0 | 10.9 | < 0.001 |
Current smoker, % | 7.1 | 11.0 | 10.0 | 10.8 | < 0.001 |
Current drinker, % | 41.9 | 44.0 | 46.2 | 35.8 | 0.08 |
Regular exercise, % | 43.3 | 38.0 | 35.4 | 36.9 | < 0.001 |
APOE ε4 carrier, % | 20.2 | 13.0 | 12.9 | 15.6 | < 0.001 |
Depression, % | 1.1 | 0.9 | 1.1 | 1.8 | 0.16 |
