Table 4 Clinical state differences between parallel-CPM responders and non-responders (only data for the parallel paradigm are shown).

From: Conditioned pain modulation (CPM) paradigm type affects its sensitivity as a biomarker of fibromyalgia

 

CPM responder (N = 13)

CPM Non responder (N = 10)

Mann–whitney-U Z score

Sig

BDI

13.85 (± 6.19)

17.70 (± 7.12)

− 1.123

0.261

FIQ-R

38.12 (± 18.03)

60.18 (± 26.18)

− 1.985

0.047*

SSS

6.85 (± 1.41)

8.50 (± 2.32)

− 1.766

0.077

WPI

11.08 (± 4.15)

6.90 (± 4.31)

− 2.030

0.042*

SF-36

52.26 (± 13.21)

42.64 (± 16.93)

− 1.488

0.137

Intensity of fatigue-previous week (VAS)

6.23 (± 1.69)

7.30 (± 2.16)

− 1.923

0.055

Intensity of numbness—previous week (VAS)

6.08 (± 3.57)

6.40 (± 4.09)

− 0.317

0.751

Intensity of pain- previous week (VAS)

4.77 (± 2.49)

6.30 (± 3.16)

− 1.467

0.142

Intensity of pain- previous month (VAS)

5.15 (± 1.19)

6.30 (± 3.23)

− 1.407

0.159

PPT (Kgf/cm2)

1.22 (± 0.86)

1.33 (± 0.38)

− 1.430

0.153

CPM (Kgf/cm2)

0.64 (± 0.42)

-0.14 (± 0.41)

− 3.522

 < 0.001

  1. BDI Beck depression inventory, FIQ-R Fibromyalgia impact questionnaire –revised, SSS Symptom severity Scale, WPI: Widespread Pain Index; SF36 Short form health survey, VAS Visual analogue scale, PPT Pressure pain threshold, measured in kgf/cm2.
  2. *The significance level was not maintained after Bonferroni-Holm correction. Significant values are in bold.
Back to article page