Figure 4
Gene ontology, signaling pathway and network analyses in HCC. Top 10 enriched biological processes, cellular components and molecular functions in (a) HCC and (b) CHB compared to healthy individuals. The most significant pathways of (c) HCC vs. healthy controls and (d) CHB vs. healthy controls. (e) PPI network of DEGs in HCC was created using Cytoscape (3.9.1). The network consists of 96 nodes and 107 edges. The size of the nodes corresponds to absolute log2(fold change). Blue and red border lines indicate the upregulated and downregulated genes, respectively. Yellow balls represent the hub genes of the network based on the betweenness, closeness, degree, eccentricity, radiality, and stress centralities.
