Figure 1
From: Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice
SPA was increased in liver tissues of mice with a western diet. Male mice fed a Chow or Western diet (W-D) for 8 weeks. (A) H&E staining of liver sections (CV—Central vein; red arrow—portal vein; yellow arrow—hepatocyte degeneration; black arrow—fat deposits). (B) Oil Red-O staining of liver sections. (C) Liver index shown as percentage of liver/body weight. (D) Hepatic SPA expression detected by Western blot. (E) Quantification of hepatic SPA protein expression shown in (D) by normalizing to GAPDH. (F) Immunofluorescent staining of SPA (green) in liver tissues. Nuclei was stained with DAPI (blue).
