Figure 3
From: Surfactant protein A promotes western diet-induced hepatic steatosis and fibrosis in mice
Fatty acid uptake was reduced in western-diet fed SPA−/− mice. Relative mRNA expression of genes regulating fatty acid homeostasis was detected by qRT-PCR and normalized to cyclophilin expression in the liver of WT or SPA−/− mice fed Chow or W-D for 8 weeks. (A) Cluster of differentiation 36 (CD36). (B) Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ). (C) Fatty Acid Synthase (FASn). (D) Stearoyl-CoA desaturase 1 (SCD1). (E) Carnitine Palmitoyltransferase-1 (CPT1). (F) Peroxisome Proliferator Activated Receptor-γ (PPAR-α).
