Table 4 Univariate and multivariate analyses of the factor associated with any stroke recurrence.
From: Long-term outcomes of patients with embolic stroke of undetermined source according to subtype
Univariable analysis | Multivariable analysis | |||
|---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Demographics | ||||
Age, year | 1.029 (1.009–1.050) | 0.005 | 1.016 (0.994–1.039 | 0.153 |
Sex, men | 1.814 (1.049–3.137) | 0.033 | 1.386 (0.780–2.463) | 0.265 |
Risk factors | ||||
Hypertension | 1.441 (0.823–2.523) | 0.200 | ||
Diabetes | 1.806 (1.113–2.929) | 0.017 | 1.505 (0.914–2.478) | 0.108 |
Hypercholesterolemia | 1.195 (0.664–2.150) | 0.553 | ||
Current smoker | 0.709 (0.394–1.276) | 0.252 | ||
Previous stroke | 3.480 (2.119–5.714) | < 0.001 | 2.884 (1.716–4.847) | < 0.001 |
Initial NIHSS score | 0.984(0.912–1.062) | 0.679 | ||
Laboratory findings | ||||
White blood cell | 1.000 (1.000–1.000) | 0.592 | ||
Platelet | 0.994 (0.990–0.998) | 0.007 | 0.996 (0.992–1.001) | 0.093 |
Total cholesterol | 0.998(0.993–1.003) | 0.504 | ||
Triglyceride | 1.001 (0.999–1.003) | 0.464 | ||
HDL | 0.979 (0.956–1.003) | 0.083 | ||
LDL | 0.997 (0.990–1.004) | 0.386 | ||
ESUS classification | ||||
Minor cardioembolic source | Ref | 0.044 | Ref | 0.177 |
No cause | 1.281 (0.637–2.577) | 0.487 | 1.292 (0.639–2.613) | 0.475 |
Two or more causes | 1.389 (0.685–2.819) | 0.362 | 1.084 (0.528–2.229) | 0.825 |
Non-stenotic (< 50%) relevant artery plaque | 1.433 (0.601–3.417) | 0.417 | 1.056 (0.439–2.543) | 0.903 |
Complex aortic plaque | 3.220 (1.486–6.977) | 0.003 | 2.470 (1.108–5.508) | 0.027 |
