Table 1 Stability of bortezomib (2.5 mg/mL) in storage containers (vials and syringes) at 5 ± 3 °C in the dark (all data are presented as the mean ± S.D. of test results for all analysed samples from 3 different vials or syringes and 2 samples withdrawn from each preparation (n = 6)).
From: Physicochemical stability of bortezomib solutions for subcutaneous administration
Sample type | Initial drug concentration (mg/mL) Mean ± S.D | Drug concentration remaining (%) Mean ± S.D | ||||
|---|---|---|---|---|---|---|
1 day | 3 days | 4 days | 7 days | 10 days | ||
Glass vial | 2.46 ± 0.01 | 99.75 ± 0.26 | 97.59 ± 0.54 | 98.05 ± 0.35 | 95.89 ± 0.33 | 91.56 ± 0.60 |
Polypropylene syringes | 2.45 ± 0.04 | 100.76 ± 0.24 | 98.02 ± 0.62 | 97.62 ± 0.68 | 95.84 ± 0.41 | 91.02 ± 0.53 |
