Table 4 Means and two-way ANOVA outputs from a linear model, lm(gene ~ sex × treatment), indicating sex specific effect of dietary restriction on expression of liver mTOR pathway genes across the 2-week restriction period.

From: Dietary restriction reveals sex-specific expression of the mTOR pathway genes in Japanese quails

Response variables

Treatment means

p-values

Sex

ADL

DR20

DR30

DR40

Sex

Treatment

Treatment × sex

mTOR

Female

3.13

2.20

1.34

0.99

0.029

 < 0.001

0.021

Male

2.23

1.46

1.40

1.21

RPS6K1

Female

1.25

1.88

2.34

2.48

0.212

 < 0.001

0.005

Male

0.60

2.99

2.97

2.29

ATG9A

Female

0.77

1.01

1.03

1.60

 < 0.001

 < 0.001

0.041

Male

1.03

1.74

2.14

1.81

IGF1

Female

5.19

2.85

2.53

3.44

 < 0.001

 < 0.001

0.075

Male

3.66

1.72

1.91

1.01

IGF1R

Female

2.13

1.60

1.67

1.72

0.895

0.01

0.132

Male

2.39

1.83

2.02

0.98

GHR

Female

2.10

2.41

3.89

3.82

0.34

 < 0.001

0.437

Male

2.40

2.37

3.28

3.33

  1. mTOR mechanistic target of rapamycin, RPS6K1 ribosomal protein S6 kinase 1, ATG9A autophagy-related 9A, IGF1 insulin-like growth factor 1, IGF1R insulin-like growth factor 1 receptor, GHR growth hormone receptor, ADL ad libitum, DR20 20% restriction, DR30 30% restriction, DR40 40% restriction.
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