Figure 2

Gait Speed Heatmap. 20 significant metabolites visually resulted in a less striking difference in metabolite concentrations when comparing slow gait speed (Blue) to fast gait speed (Green). The 20 significant metabolites consisted of acylcarnitines (C5, C5:1, C7, C9, PE 34:0), organic acids and derivatives (prolyl-glycine, ornithine, taurine, N-acetylputrescine, N-acetylcarnosine, creatine, 2-hydroxyglutarate, citrulline, valine), organic nitrogen compounds (trimethylamine-n-oxide), benzenoids (hydroxyectoine), nucleic acid (urate), carbohydrate (sucrose), lipid and lipid-like molecules (Butyrobetaine) (and phosphocholine. We have included the heatmap of the selected 20 metabolites to provide a visual depiction of the qualitative differences; there was a lack of stark differences depicted between those with slow versus fast gait speed.