Table 3 Association between Na/Cl ratio and in-hospital mortality in multiple regression model.

From: Positive association between sodium-to-chloride ratio and in-hospital mortality of acute heart failure

 

Model I

Model II

Model III

Model IV

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

HR (95% CI)

P value

Na/Cl ratioa

 In-hospital mortality

1.30 (1.18–1.43)

 < 0.001

1.35 (1.22–1.49)

 < 0.001

1.44 (1.31–1.59)

 < 0.001

1.34 (1.2–1.5)

 < 0.001

 

Na/Cl ratio tertiles

 In-hospital mortality

Q1

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

1 (Ref)

 

Q2

1.25 (1.04–1.5)

0.019

1.22 (1.02–1.47)

0.033

1.36 (1.13–1.64)

0.001

1.3 (1.07–1.57)

0.008

Q3

1.46 (1.23–1.74)

 < 0.001

1.51 (1.27–1.8)

 < 0.001

1.72 (1.44–2.06)

 < 0.001

1.54 (1.26–1.88)

 < 0.001

P fortrend

 

 < 0.001

 

 < 0.001

 

 < 0.001

 

 < 0.001

  1. aNA/CL ratio was entered as continuous variable per 0.1 increase.
  2. Model I: didn’t adjusted for confounders.
  3. Model II: adjusted for age, sex.
  4. Model III: Model II + myocardial infarction, COPD, diabetes, chronic kidney disease, liver disease, CCI, APSIII.
  5. Model IV: Model III + heart rate, mean blood pressure, glucose, blood urea nitrogen, serum calcium, serum potassium, eGFR, white cell count, hemoglobin, platelets, bicarbonate.
Back to article page