Table 1 Results of the meta-analysis and CSRM system collection.
From: Feasibility analysis of China's medical insurance coverage of assisted reproductive technology
Group | Number of studies | Sample size | Analyzed value |
|---|---|---|---|
Topic A: Prevalence of infertility in China | Infertility rate (95%CI) | ||
Entire couples (female age 20–49) of one-year infertility | 19 | 8,022,162 | 0.042 (0.038–0.046) |
Entire couples (female age 20–49) of two-year infertility | 6 | 6,023,427 | 0.015 (0.013–0.018) |
Risk couples (female age 20–49) of one-year infertility | 25 | 266,662 | 0.153 (0.133–0.172) |
Risk couples (female age 20–49) of two-year infertility | 9 | 160,256 | 0.089 (0.068–0.110) |
Entire couples (female age 20–24) of one-year infertility | 6 | 20,383 | 0.045 (0.021–0.069) |
Entire couples (female age 25–29) of one-year infertility | 6 | 8351 | 0.047 (0.029–0.064) |
Entire couples (female age 30–34) of one-year infertility | 5 | 5607 | 0.048 (0.025–0.070) |
Entire couples (female age 35–39) of one-year infertility | 4 | 5184 | 0.035 (0.018–0.052) |
Entire couples (female age 40–49) of one-year infertility | 5 | 5069 | 0.032 (0.010–0.054) |
Entire couples (female age 20–24) of two-year infertility | 3 | 22,644 | 0.025 (0.023–0.027)* |
Entire couples (female age 25–29) of two-year infertility | 3 | 81,304 | 0.018 (0.013–0.024) |
Entire couples (female age 30–34) of two-year infertility | 3 | 116,933 | 0.011 (0.010–0.012)* |
Entire couples (female age 35–39) of two-year infertility | 3 | 369,540 | 0.011 (0.006–0.017) |
Entire couples (female age 40–49) of two-year infertility | 3 | 371,238 | 0.010 (0.006–0.015) |
Risk couples (female age 20–24) of one-year infertility | 11 | 22,538 | 0.143 (0.111–0.174) |
Risk couples (female age 25–29) of one-year infertility | 8 | 25,740 | 0.148 (0.108–0.189) |
Risk couples (female age 30–34) of one-year infertility | 10 | 16,396 | 0.165 (0.115–0.215) |
Risk couples (female age 35–39) of one-year infertility | 9 | 26,180 | 0.209 (0.159–0.259) |
Risk couples (female age 40–49) of one-year infertility | 10 | 22,256 | 0.220 (0.161–0.280) |
Risk couples (female age 20–24) of two-year infertility | 3 | 45,152 | 0.090 (0.047–0.134) |
Risk couples (female age 25–29) of two-year infertility | 3 | 23,189 | 0.103 (0.066–0.140) |
Risk couples (female age 30–34) of two-year infertility | 2 | 13,466 | 0.123 (0.097–0.148) |
Risk couples (female age 35–39) of two-year infertility | 2 | 13,541 | 0.132 (0.126–0.137)* |
Risk couples (female age 40–49) of two-year infertility | 2 | 7366 | 0.126 (0.098–0.153) |
Topic B: Success rate of ART in China | Live birth rate (95%CI) | ||
Livebirth rate of Meta | |||
First complete cycle | 4 | 75,177 | 0.517 (0.431–0.604) |
Second complete cycle | 4 | 14,466 | 0.377 (0.333–0.421) |
Third complete cycle | 4 | 3530 | 0.236 (0.148–0.324) |
Fourth complete cycle | 4 | 1412 | 0.189 (0.169–0.210)* |
First transfer cycle of a complete cycle | 3 | 34,918 | 0.417 (0.395–0.438) |
Second transfer cycle of a complete cycle | 3 | 5053 | 0.310 (0.165–0.454) |
≥ Third transfer cycles of a complete cycle | 3 | 1176 | 0.274 (0.121–0.428) |
Livebirth rate of CSRM | |||
Transfer cycle | – | 1,583,021 | 0.404 (–) |
Fresh embryo transfer | – | 667,542 | 0.419 (–) |
Frozen embryo transfer | – | 915,479 | 0.393 (–) |
Transfer cycle of 18–34 women | – | 622,066 | 0.455 (–) |
Transfer cycle of 35–40 women | – | 197,196 | 0.318 (–) |
Transfer cycle of 41–44 women | – | 39,531 | 0.119 (–) |
Transfer cycle of 45–49 women | – | 6916 | 0.042 (–) |
Multiple birth rate | – | 638,802 | 0.254 (–) |
Topic C: Cost per live birth of ART in China^ | Cost (95%CI) | ||
Per live birth | 21 | 21,567 | 67,002 (62,101–71,903) |
Per initiated cycle | 21 | 21,567 | 22,120 (20,512–23,729) |
Per frozen-thawed embryo transfer cycle | 2 | 1551 | 5985 (2383–9586) |
Per live birth of GnRH-a long protocol | 16 | 15,494 | 61,866 (56,273–67,459) |
Per live birth of GnRH-ant protocol | 11 | 4408 | 63,468 (50,504–76,433) |
Per live birth of minimal-stimulation protocol | 6 | 593 | 70,006 (51,732–88,280) |
Per live birth of PPOS protocol | 3 | 292 | 70,072 (3905–136,239) |
Per live birth of natural cycle protocol | 1 | 374 | 269,912 (–) |
Per live birth of 20–34 years old | 7 | 12,189 | 54,165 (46,728–61,601)# |
Per live birth of 35–49 years old | 8 | 4646 | 89,935 (75,239–104,632) |
Per live birth of 2000–2010 | 3 | 360 | 63,934 (42,348–85,519)# |
Per live birth of 2011–2021 | 18 | 21,207 | 67,376 (62,230–72,521) |
Per initiated cycle of GnRH-a long protocol | 16 | 15,494 | 25,140 (22,967–27,313) |
Per initiated cycle of GnRH-ant protocol | 11 | 4408 | 21,883 (19,464–24,301) |
Per initiated cycle of minimal-stimulation protocol | 6 | 593 | 16,178 (12,167–20,190) |
Per initiated cycle of PPOS protocol | 3 | 292 | 14,496 (7443–21,550) |
Per initiated cycle of natural cycle protocol | 1 | 374 | 12,254 (–) |
Per initiated cycle of 20–34 years old | 7 | 12,189 | 22,662 (20,651–24,673) |
Per initiated cycle of 35–49 years old | 8 | 4646 | 21,004 (19,158–22,851) |
Per initiated cycle of 2000–2010 | 3 | 360 | 19,155 (10,486–27,824) |
Per initiated cycle of 2011–2021 | 18 | 21,207 | 22,469 (20,790–24,149) |
