Figure 3
From: Modified polymeric biomaterials with antimicrobial and immunomodulating properties
Effect of CecA and Pur on the cell proliferation and cytotoxicity in 2D cultures (A–B) and 3D cultures: direct (C–D) and indirect (E–F) tests, measured with MTT (proliferation) and LDH (cytotoxicity) methods; statistically significant results compared to the control are indicated with ‘*’ and those compared to the medium are marked with “#”: *—p < 0.05, **—p < 0.01, ***—p < 0.001 (One-Way ANOVA, Dunnett’s test). control – PPmesh (unmodified), commercial prosthesis; CecA-PPmesh—prosthesis modified with cecropin A; Pur-PPmesh—prosthesis modified with puromycin; medium—extract prepared without the prosthesis.
