Table 3 Clinical characteristics and biomarkers of the patients.
From: A new dynamic nomogram for predicting the risk of severe Mycoplasma pneumoniae pneumonia in children
Variables | All (n = 526) | Training cohort | p | Validation cohort | p | ||
|---|---|---|---|---|---|---|---|
GMPP (n = 200) | SMPP (n = 221) | GMPP (n = 48) | SMPP (n = 57) | ||||
Biomarkers | |||||||
WBC, 109/L | 8.95 (7.03,12.05) | 8.59 (6.25,11.69) | 9.64 (7.51,12.82) | 0.006 | 8.65 (7.31,10.23) | 8.39 (6.32,11.68) | 0.622 |
N%, % | 62.50 (48.80,75.50) | 59.70 (46.28,69.13) | 67.75 (49.88,80.38) | < 0.001 | (57.94 ± 15.89) | (63.56 ± 18.29) | 0.207 |
L%, % | 29.60 (18.55,41.75) | 32.55 (24.28,45.40) | 25.30 (15.33,40.15) | < 0.001 | 34.70 (24.10,39.60) | 28.25 (15.73,37.45) | 0.069 |
NLR | 2.12 (1.17,4.03) | 1.82 (1.00,2.87) | 2.68 (1.20,5.20) | < 0.001 | 1.71 (1.30,2.92) | 2.35 (1.45,4.90) | 0.067 |
AGR | 1.66 (1.38,2.00) | 1.83 (1.57,2.08) | 1.51 (1.23,1.87) | < 0.001 | (1.86 ± 0.46) | (1.58 ± 0.49) | 0.606 |
CRP, mg/L | 6.60 (0.80,23.27) | 4.16 (0.50,12.60) | 13.45 (2.40,40.13) | < 0.001 | 5.36 (0.80,23.07) | 7.30 (0.80,39.95) | 0.330 |
ESR, mm/h | 35.00 (20.00,52.50) | 29.00 (18.00,40.50) | 40.00 (20.25,61.00) | < 0.001 | (34.50 ± 20.89) | (38.54 ± 19.94) | 0.721 |
MPV, fL | 9.40 (8.90,10.00) | 9.30 (8.88,9.80) | 9.60 (9.00,10.30) | 0.002 | 9.10 (8.70,9.70) | 9.35 (8.70,10.00) | 0.344 |
Clinical characteristics | |||||||
Age, months | 52.00 (27.00,83.00) | 60.00 (36.00,84.00) | 44.00 (21.00,78.75) | 0.004 | 51.00 (33.00,71.00) | 43.00 (25.50,84.00) | 0.526 |
Sex | 294 (55.89%) | 0.503 | 0.232 | ||||
Female | 232 (44.11%) | 84 (42.00%) | 100 (45.20%) | 25 (52.10%) | 23 (40.40%) | ||
Male | 294 (55.89%) | 116 (58.00%) | 121 (54.80%) | 23 (47.90%) | 34 (59.60%) | ||
Primary disease | 60 (11.41%) | < 0.001 | 0.297 | ||||
No | 191 (95.50%) | 180 (81.40%) | 45 (93.80%) | 50 (87.70%) | |||
Yes | 9 (4.50%) | 41 (18.60%) | 3 (6.30%) | 7 (12.30%) | |||
Coinfection | 246 (46.77%) | < 0.001 | < 0.001 | ||||
No | 131 (65.50%) | 104 (47.10%) | 29 (60.40%) | 16 (28.10%) | |||
Yes | 69 (34.50%) | 117 (52.90%) | 19 (39.60%) | 41 (71.90%) | |||
Pleural effusion | 146 (27.76%) | < 0.001 | 0.065 | ||||
No | 158 (79.00%) | 141 (63.80%) | 41 (85.40%) | 40 (70.20%) | |||
Yes | 42 (21.00%) | 80 (36.20%) | 7 (14.60%) | 17 (29.80%) | |||
Fever days | 362 (68.82%) | < 0.001 | < 0.001 | ||||
< 7 | 91 (45.50%) | 39 (17.60%) | 24 (50.00%) | 10 (17.50%) | |||
≥ 7 | 109 (54.50%) | 182 (82.40%) | 24 (50.00%) | 47 (82.50%) | |||
Wheeze | 153 (29.09%) | < 0.001 | 0.006 | ||||
No | 164 (82.00%) | 138 (62.40%) | 39 (81.30%) | 32 (56.10%) | |||
Yes | 36 (18.00%) | 83 (37.60%) | 9 (18.80%) | 25 (43.90%) | |||
