Table 3 Univariate and multivariable logistic regression analysis for segmental glomerular sclerosis according to the clinical parameters and lesion in FSGS patients.
From: A new index for the outcome of focal segmental glomerulosclerosis
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Odds ratio | P-value | Odds ratio | P-value | |
Group 2–1 | 6.509 | 0.001 | 1.190 | 0.032 |
Clinical parameters at biopsy | ||||
Gender | 2.224 | 0.121 | ||
Age | 0.997 | 0.867 | ||
Course of disease | 0.996 | 0.521 | ||
u-RBC | 1.000 | 0.561 | ||
UP | 1.000 | 0.252 | ||
Creatinine | 1.009 | 0.008 | 1.008 | 0.023 |
CKD stage | ||||
CKD2 | 0.500 | 0.661 | ||
CKD3 | 1.500 | 0.810 | ||
CKD4 | 1.000 | 1.000 | ||
Histology lesions | ||||
GSR | 0.236 | 0.074 | ||
SSR | 1.081 | 0.001 | ||
CR | 1.519 | 0.206 | ||
SGR | 0.993 | 0.827 | ||
Synaptopodin intensity | 1.285 | 0.466 | ||
Foot process effacement | 1.220 | 0.003 | 1.706 | 0.155 |
C score | ||||
C1 | 0.135 | 0.110 | ||
C2 | 0.063 | 0.087 | ||
T score | ||||
T1 | 0.000 | 0.998 | 0.565 | 0.607 |
T2 | 0.091 | 0.011 | 4.078 | 0.258 |
C4d score | ||||
C4d-1 | 0.952 | 0.683 | ||
C4d-2 | 5.830 | 0.098 | ||
Treatment | ||||
Glucocorticoids | 0.233 | 0.030 | 0.027 | 0.152 |
Immunosuppressants | 0.326 | 0.300 | ||
ACEI/ARB | 4.048 | 0.037 | 4.630 | 0.093 |
