Figure 8 | Scientific Reports

Figure 8

From: MMPs-related risk model identification and SAA1 promotes clear cell renal cell carcinoma migration via ERK-AP1-MMPs axis

Figure 8

SAA1 promotes ccRCC cell migration via ERK-AP1-MMPs axis. (A) Expression of SAA1, ERK1/2, phosphorylated ERK1/2/, c-Jun, and β-actin detected after transfection with siRNA in Caki-1, OSRC-2 and A498 cell lines using western blotting. (B–D) The wound-healing assay and quantification of wound-healing assay data. (E) The transwell assay and quantification of transwell migration assay data. (F) RT-qPCR analysis of key MMPS marker (MMP7, MMP9, MMP13, MMP15, MMP17, MMP19).

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