Table 1 Physicochemical features of niosomal formulations in Hepes Buffer and artificial urine medium: vesicle dimensions (Hydrodynamic Diameter), ζ-Potential, polydispersity index (PDI), and concentration of entrapped gentamicin in niosomes (GM-entrapment in mg/ml)
From: Gentamicin loaded niosomes against intracellular uropathogenic Escherichia coli strains
Sample | Hydrodynamic Diameter (nm) ± SD | ζ-Potential (mV) ± SD | PDI ± SD | GM-entrapment (mg/ml) | ||||
---|---|---|---|---|---|---|---|---|
Hepes buffer | AUM | Hepes buffer | AUM | Hepes buffer | AUM | Hepes buffer | AUM | |
Nio | 101.60 ± 3.20 | 111.40 ± 1.20 | -35.60 ± 2.10 | -9.80 ± 0.12 | 0.28 ± 0.02 | 0.26 ± 0.01 | – | – |
GM-Nio | 211.10 ± 3.50 | 196.10 ± 1.10 | -37.10 ± 1.40 | -10.90 ± 2.12 | 0.20 ± 0.01 | 0.17 ± 0.03 | 1.00 ± 0.01 | 1.00 ± 0.01 |