Figure 5

DSRGs expression profiles of OS subclusters in cell components of the OS TME. (A) Heatmap shows the top differentially expression genes in each OS cluster. (B) t-SNE scatter plot showing the expression level of each DSRG in OS subclusters. (C) Violin plot showing the expression level of DSRGs in OS subclusters. (D) Heatmap shows expression patterns of DSRGs in a pseudotime trajectory profile, the genes are classified into 6 clusters according to the expression pattern.