Table 2 Body size and composition at birth.

From: The impact of CREBRF rs373863828 Pacific-variant on infant body composition

Outcomes

Infant CREBRF rs373863828 genotype

Adjusted model 1

aMD or aOR (95% CI)

P

Adjusted model 2

aMD or aOR (95% CI)

P

A/G or A/A

N

G/G

N

Body size

 Length z-score

1.07 (1.12)

18

0.78 (0.90)

49

0.30 (−0.22, 0.81)

0.26

0.36 (−0.21, 0.94)

0.22

 Weight z-score

1.18 (1.19)

18

0.75 (0.89)

49

0.45 (−0.07, 0.97)

0.09

0.42 (−0.16,1.00)

0.16

Small for gestational age

 Population

0 (0.0%)

18

0 (0.0%)

49

-

-

-

-

 Customized

0 (0.0%)

18

1 (2.0%)

49

-

-

-

-

Large for gestational age

 Population

8 (44.4%)

18

12 (24.5%)

49

2.42 (0.70, 8.38)

0.16

2.68 (0.69, 9.57)

0.16

 Customized

4 (22.2%)

18

6 (12.2%)

49

2.72 (0.56, 13.25)

0.21

4.75 (0.75, 30.2)

0.10

Body composition

 BMI, kg/m2

14.3 (2.0)

18

14.0 (1.1)

49

0.4 (−0.4, 1.3)

0.29

0.3 (−0.5, 1.1)

0.46

 z−score

0.77 (1.14)

18

0.50 (0.76)

49

0.28 (−0.18, 0.75)

0.24

0.24 (−0.27, 0.75)

0.10

Skinfold thickness, mm

 Triceps

6.8 (1.7)

16

6.5 (1.6)

45

0.4 (−0.5, 1.3)

0.38

0.3 (−0.6, 1.3)

0.47

 Subscapular

6.7 (1.8)

16

5.7 (1.4)

45

0.7 (−0.1, 1.6)

0.09

0.5 (−0.4, 1.4)

0.24

Arm muscle cross-sectional area, cm2

8.1 (6.8)

16

7.7 (7.4)

45

1.6 (−2.0, 5.2)

0.38

0.9 (−2.9, 4.6)

0.65

Whole body FM, kg

0.4 (0.2)

12

0.5 (0.2)

25

0.0 (−0.2, 0.1)

0.52

0.0 (−0.2, 0.1)

0.38

FMI, kg/m2

1.6 (0.7)

12

1.8 (0.8)

25

−0.2 (−0.7, 0.3)

0.37

−0.3 (−0.9, 0.2)

0.19

Whole body LM, kg

3.4 (0.7)

12

3.3 (0.3)

25

0.2 (−0.1, 0.5)

0.18

0.3 (0.0, 0.6)

0.10

LMI, kg/m2

12.5 (1.4)

12

12.2 (0.8)

25

0.4 (−0.3, 1.1)

0.23

0.5 (−0.3, 1.3)

0.19

  1. Data are number (percent) or mean (standard deviation). Z-scores specific for gestation and sex. Model 1: adjusted for potential confounding by gestational age, sex, ethnicity and parity. Model 2: adjusted for potential confounding by gestational age, sex, ethnicity, parity and mediation by gestational diabetes (International Association of Diabetes in Pregnancy Study Groups diagnostic thresholds).
  2. FM fat mass, FMI fat mass index, LM lean mass, LMI lean mass index.