Table 3 Logistic regression analysis of lineage 3 compared with lineage 4 by demographic, clinical variable, drug resistance and regions.
From: Population structure and spatial distribution of Mycobacterium tuberculosis in Ethiopia
Variables | L3 | L4 | COR [95% CI] | p-value | AOR [95% CI] | p-value | |
|---|---|---|---|---|---|---|---|
Sex | Male | 132 | 427 | 1.319 [1.034, 1.682] | 0.026 | 1.372 [1.061, 1.774] | 0.016 |
Female | 256 | 628 | Ref | Ref | |||
Age group | < 15 | 11 | 35 | 0.821[0.344, 1.956] | 0.655 | NA | |
15–24 | 132 | 389 | 0.886[0.497, 1.579] | 0.682 | NA | ||
25–34 | 131 | 335 | 1.021[0.572, 1.823] | 0.944 | NA | ||
35–44 | 70 | 160 | 1.142[0.620, 2.106] | 0.670 | NA | ||
45–54 | 24 | 87 | 0.720[0.355, 1.460] | 0.363 | NA | ||
55 + | 18 | 47 | Ref | ||||
Treatment history | Retreatment | 83 | 157 | 1.557[1.158, 2.093] | 0.003 | 1.388 [1.000, 1.924] | 0.050 |
New | 305 | 898 | Ref | Ref | |||
HIV status | Positive | 83 | 144 | 1.715[1.267, 2.320] | < 0.001 | 1.313 [0.940, 1.832] | 0.110 |
Unknown | 27 | 84 | 0.956 [0.607, 1.506] | 0.847 | 0.940 [0.579, 1.525] | 0.802 | |
Negative | 278 | 827 | Ref | Ref | |||
Regions | Addis Ababa | 51 | 108 | 1.181 [0.662, 2.106] | 0.574 | 1.437 [0.789, 2.617] | 0.236 |
Afar | 14 | 37 | 0.946 [0.435, 2.055] | 0.888 | 1.049 [0.476, 2.314] | 0.905 | |
Amhara | 37 | 68 | 1.360 [0.732, 2.529] | 0.331 | 1.599 [0.844, 3.029] | 0.150 | |
Benishangul G | 3 | 14 | 0.536 [0.141, 2.033] | 0.359 | 0.692 [0.180, 2.659] | 0.592 | |
Gambella | 60 | 40 | 3.750 [2.018, 6.970] | < 0.001 | 4.374 [2.315, 8.265] | < 0.001 | |
Harar | 15 | 35 | 1.071 [0.497, 2.310] | 0.860 | 1.283[0.585, 2.811] | 0.534 | |
Oromia | 82 | 354 | 0.579 [0.341, 0.985] | 0.044 | 0.689 [0.398, 1.191] | 0.182 | |
SNNPR | 42 | 256 | 0.410 [0.231, 0.729] | 0.002 | 0.507 [0.279, 0.922]* | 0.026 | |
Somali | 28 | 57 | 1.228 [0.638, 2.364] | 0.539 | 1.495 [0.762, 2.933] | 0.242 | |
Tigray | 32 | 26 | 3.077 [1.526, 6.204] | 0.002 | 3.444 [1.685, 7.037] | 0.001 | |
Dire Dawa | 24 | 60 | Ref | Ref | |||
Rifampicin resistance | Yes | 18 | 43 | 1.151 [0.654, 2.024] | 0.626 | NA | |
No | 326 | 896 | Ref | ||||
Isoniazid resistance | Yes | 14 | 43 | 0.884 [0.477, 1.637] | 0.695 | NA | |
No | 330 | 896 | Ref |
