Table 4 Univariable and multivariable analyses of prognostic indicators by Cox regression model in the TCGA cohort.
Variable | n/EPV | Univariable analysis | Multivariable analysis | ||||||
|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | ||||
L | U | L | U | ||||||
CCNF (high vs low) | 218/111_257/47 | 3.52 | 2.50 | 4.96 | < 0.0001 | 2.86 | 2.02 | 4.06 | < 0.0001 |
Age (> 60 vs ≤ 60) | 236/83_239/75 | 1.06 | 0.77 | 1.44 | 0.74 | – | – | – | – |
Sex (male vs female) | 312/101_163/57 | 0.95 | 0.68 | 1.31 | 0.74 | – | – | – | – |
Tumor grade (G3–G4 vs G1–G2) | 261/99_214/59 | 1.36 | 0.98 | 1.87 | 0.06 | – | – | – | – |
pT status (T3–T4 vs T1–T2) | 177/96_298/62 | 3.19 | 2.31 | 4.39 | < 0.0001 | – | – | – | – |
pN− | 225/78 | Ref | – | – | – | – | |||
pN+ | 15/11 | 3.78 | 2.01 | 7.13 | < 0.0001 | – | – | – | – |
pNx | 235/69 | 0.83 | 0.60 | 1.15 | 0.26 | – | – | – | – |
M status (M1 vs M0) | 69/56_406/102 | 4.23 | 3.05 | 5.86 | < 0.0001 | – | – | – | – |
TNM stage (III–IV vs I–II) | 191/105_284/53 | 3.61 | 2.59 | 5.02 | < 0.0001 | 2.96 | 2.11 | 4.14 | < 0.0001 |
